Cocaine - Metabolism and excretion, detect in urine
Cocaine is extensively metabolized, primarily in the liver, with only about 1% excreted unchanged in the urine. The metabolism is dominated by hydrolytic ester cleavage, so the eliminated metabolites consist mostly of benzoylecgonine, the major metabolite, and in lesser amounts ecgonine methyl ester and ecgonine.
If taken with alcohol, cocaine combines with the ethanol in the liver to form cocaethylene, which is both more euphorigenic and has higher cardiovascular toxicity than cocaine by itself.
Cocaine metabolites are detectable in urine for up to four days after cocaine is used. Benzoylecgonine can be detected in urine within four hours after cocaine inhalation and remains detectable in concentrations greater than 1000 ng/ml for as long as 48 hours. Detection in hair is possible in regular users until the sections of hair grown during use are cut or fall out.
Fast COC/Cocaine Detox Kit for People Under 200 Lbs
Fast COC/Cocaine Detox Kit for People Over 200 Lbs
2 Step COC/Cocaine Detox Program for Persons over 200 LBS
2 Step COC/Cocaine Detox Program for persons under 200 LBS
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