TCA, Tricyclic Antidepressants
Drug Name: Tricyclic Antidepressants
Drug Abbreviation: TCA
Drug Slang Term(s): Vivactil, Anafranil, Janimine, Tofranil
Drug Screening Cut-off in Urine: 1,000 ng/mL
Drug Information:
TCA (Tricyclic Antidepressants) are commonly used for the treatment of depressive disorders. TCA overdoses can result in profound central nervous system depression, cardiotoxicity and anticholinergic effects. TCA overdose is the most common cause of death from prescription drugs. TCAs are taken orally or sometimes by injection. TCAs are metabolized in the liver. Both TCAs and their metabolites are excreted in urine mostly in the form of metabolites for up to ten days.
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